DEPARTMENT: Editorial pointers
DEPARTMENT: News track
COLUMN: The profession of IT
Many networks, physical and social, are complex and scale-invariant. This has important implications from the spread of epidemics and innovations to protection from attack.
Peter J. Denning
DEPARTMENT: Hot links
COLUMN: Practical programmer
Assembling the individual pieces to form an integrated component architecture.
Robert L. Glass
Exporting IT jobs and importing IT workers not only harms U.S. IT workers, it also harms U.S. firms and the broader economy.
SPECIAL ISSUE: Bioinformatics: transforming biomedical research and medical care
Bioinformatics and computational biology will enable breakthroughs in basic biological research and improvements in the prevention, treatment, and cure of diseases.
Craig A. Stewart
Understanding evolution and the basic structure and function of proteins are two grand challenge problems in biology that can be solved only through the use of high-performance computing.
David A. Bader
PetaFLOPS computers---capable of performing a thousand trillion mathematical operations per second, 25 times faster than the largest supercomputers today---will open new doors to understanding the functions of biological molecules …
Toshikazu Ebisuzaki, Robert Germain, Makoto Taiji
This open source toolkit will help scientists interpret the vast body of genomic data now publicly available.
Ross Overbeek, Terry Disz, Rick Stevens
Four biomedically oriented grid systems, ranging from SARS diagnosis to arthropod evolution, demonstrate the promise of grid computing in medical practice and biological science.
Mark Ellisman, Michael Brady, David Hart, Fang-Pang Lin, Matthias MÜller, Larry Smarr
User-centered design techniques can broaden the appeal, use, and effectiveness of Web-based bioinformatics tools.
Homa Javahery, Ahmed Seffah, Thiruvengadam Radhakrishnan
Problem-solving environments and advanced visualization take on the complexity of biomedical computing, improving its utility to scientists and clinicians alike.
Chris R. Johnson, Rob MacLeod, Steven G. Parker, David Weinstein
An analysis of risks in software development, using data from senior IT managers, produced surprising results. Our one-minute assessment tool applies those results to assessing the risks of specific projects.
Amrit Tiwana, Mark Keil
While millions of dollars have been spent building digital libraries, research indicates that millions of potential users may still be ignoring them.
James Y.L. Thong, Weiyin Hong, Kar Yan Tam
Ontology-enabled knowledge management experiences derived from a domain ontology development project at Intel Corporation are described and assessed.
Theresa Edgington, Beomjin Choi, Katherine Henson, T.S. Raghu, Ajay Vinze
Web sites that make it too cumbersome for customers to search and purchase products online will never enjoy a competitive edge. Fortunately, there are many visualization tools and techniques available that may be just what the …
Shobha Ganapathy, C. Ranganathan, Balaji Sankaranarayanan
An overview and comparison of the U.S., Japanese, and German machine tool industries.
Markus Biehl, Edmund Prater, John R. McIntyre
A study of AOL users finds they are particularly gratified using the Net as a source of information, communication, and socializing---results that may be helpful to ISPs in their efforts to attract and retain users.
Thomas F. Stafford, Dennis Gonier
COLUMN: Technical opinion
With all the excitement over the potential of nanotechnology, has any research addressed the potential toxicity nanoparticles may have on our health and environment?
Ken Donaldson, Vicki Stone
COLUMN: Inside risks
P.L. Vora, B. Adida, R. Bucholz, D. Chaum, D.L. Dill, D. Jefferson, D.W. Jones, W. Lattin, A.D. Rubin, M.I. Shamos, M. Yung