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Inexpensive 3D-Printed Microscope Can Spot Coronavirus in Blood

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he digital microscope is comprised of a laser diode, a microscope objective lens, a glass plate to induce lateral shearing of the object wavefront, and an image sensor.

A digital microscope that uses holography and deep-learning technology could detect COVID-19 in a drop of blood.

Credit: Tim O'Connor

A three-dimensionally (3D)-printed microscope could detect COVID-19 in a drop of blood through the use of digital holographic microscopy and deep learning.

Developed by scientists at the University of Connecticut (UConn), the device uses low-cost components that UConn's Bahram Javidi says are easily acquired: a camera, a laser diode, an objective lens, a glass plate, and a complementary metal-oxide semiconductor (CMOS) image sensor.

In a test of blood samples from 10 patients who tested positive for the virus and 14 health care workers who tested negative, the microscope was able to detect the coronavirus in 80% of patient samples. The test's efficacy for early detection remains unclear.

From IEEE Spectrum
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Abstracts Copyright © 2021 SmithBucklin, Washington, DC, USA


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